Unlocking Your Skin's Natural Renewal Process with Pep-Lift™
In an era where skincare transcends mere aesthetics and becomes a ritual of self-care, empowerment, and scientific precision, Derminous introduces Pep-Lift™ 24K Gold Micro-Infusion System—a revolutionary at-home anti-aging solution that bridges the gap between clinical dermatology and daily skincare. Unlike traditional microneedling or superficial serums, Pep-Lift™ leverages triple-patented bioactive ingredients, 24K gold-coated micro-needles, and a four-step renewal protocol to activate your skin’s innate regenerative capacity—safely, effectively, and without downtime[1] .

The Science Behind Skin Renewal
Human skin naturally renews itself every 28–40 days, but this process slows significantly with age, UV exposure, and environmental stressors[2] . By the time we reach our 30s, cellular turnover can decrease by up to 50%, leading to dullness, fine lines, and weakened barrier function[3] . Traditional topical products often fail to penetrate beyond the stratum corneum—the outermost layer—limiting their efficacy.

Pep-Lift™ addresses this limitation through micro-channeling technology. Its medical-grade stainless steel needles, coated in 24K gold for enhanced biocompatibility and antimicrobial properties, create transient micro-channels in the epidermis. These channels allow high-concentration actives like PDRN (Polydeoxyribonucleotide), acetyl hexapeptide-8 (Syn-Ake®), and patented niacinamide to bypass surface barriers and deliver directly into the dermal layers where collagen synthesis occurs[4] .

“Microneedling enhances transdermal delivery by up to 1,000-fold compared to passive application,” notes a 2020 review in Dermatologic Surgery[5] .
Triple-Patented Actives: Precision Anti-Aging
At the heart of Pep-Lift™ lies a synergistic serum formulation backed by three key patents:
- Class III Snake Venom Peptide (Acetyl Hexapeptide-8) – Mimics the inhibitory effect of botulinum toxin on neurotransmitter release, reducing dynamic wrinkles without paralysis. Patented under ZL202111504220.4, this peptide offers a non-invasive alternative to injectables[6] .
- PDRN (Polydeoxyribonucleotide) – A DNA-derived regenerative molecule clinically proven to accelerate tissue repair, stimulate fibroblast activity, and boost hyaluronic acid production[7] . Originally developed for wound healing, PDRN is now a gold standard in regenerative dermatology.
- Patented Niacinamide (ZL2020116206743) – Engineered for ultra-low nicotinic acid content, minimizing irritation while maximizing brightening and barrier-strengthening effects—ideal for sensitive and post-procedure skin[8] .
These ingredients work in concert to not only smooth existing lines but also reprogram skin resilience from within.
The Four-Step Ritual: From Activation to Lock-In
Pep-Lift™ isn’t just a product—it’s a curated ritual designed to mirror professional clinic protocols:
Stage 1: Micro-Activation
The 24K gold micro-infusion tip gently presses onto clean skin, creating invisible micro-channels. Gold’s natural anti-inflammatory properties reduce redness and microbial risk—a critical advantage over standard titanium needles[9] .
Stage 2: Deep Infusion
The serum, pre-loaded in a sterile vial, flows directly through the needle upon inversion. No droppers, no contamination. Users apply with light tapping motions across face, neck, and décolletage for even distribution.
Stage 3: Soothing Repair
Immediately after infusion, the Post-Treatment Repair Mask—enriched with recombinant fibronectin, mussel extract, and panthenol—is applied chilled. This step calms inflammation, reduces erythema, and accelerates barrier recovery, especially crucial for sensitive or reactive skin types[10] .
Stage 4: Nutrient Lock-In
The final step seals in actives with the Recovery & Lift Cream, featuring snow lotus stem cells, jojoba oil, and squalane. This occlusive yet breathable layer prevents transepidermal water loss (TEWL) while supporting long-term firming via acetyl tetrapeptide-11 and -9[11] .
This holistic approach ensures immediate hydration and progressive structural improvement—with visible results in as little as two weeks.





Safety, Accessibility, and Inclusivity
One of Pep-Lift™’s core innovations is its accessibility. Historically, treatments like radiofrequency, laser resurfacing, or professional microneedling required clinic visits, recovery time, and significant investment. Pep-Lift™ democratizes this experience—offering clinical-grade outcomes at home, with zero pain and no social downtime.
Moreover, the formula is free from alcohol, fragrance, parabens, and essential oils, making it suitable for post-procedure skin, rosacea-prone complexions, and even ethnic skin types prone to post-inflammatory hyperpigmentation (PIH)[12] . A patch test is recommended for first-time users, but clinical feedback shows >92% tolerance rate among sensitive skin cohorts.
Each kit contains two full treatments, aligning with the recommended usage of once every two weeks. This cadence optimizes cumulative benefits while allowing the skin adequate time to regenerate between sessions.
Why At-Home Microneedling Is Here to Stay
The global at-home beauty device market is projected to reach $13.8 billion by 2027, driven by tech-savvy consumers seeking professional results without clinic dependency[13] . Yet not all systems are equal. Many DIY rollers lack sterility, consistent needle depth, or compatible serums—leading to infection risks or subpar outcomes.
Pep-Lift™ solves these issues through single-use, sterile, CNC-manufactured tips and pre-measured, high-potency serums. Every component is designed as an integrated system—eliminating guesswork and maximizing safety.
As Dr. Emma Richards, a board-certified dermatologist, explains:
“The future of skincare is precision delivery. When you combine biomimetic peptides with controlled micro-injury, you’re not just treating symptoms—you’re triggering the skin’s own healing intelligence.”[14]
Conclusion: Beauty as a Daily Act of Empowerment
Derminous was founded on a simple yet radical belief: everyone deserves access to science-backed, transformative skincare—regardless of geography, budget, or clinic access. With Pep-Lift™, the brand delivers on that promise.
More than a product, Pep-Lift™ is an invitation—to reconnect with your skin, honor its biology, and participate actively in your renewal journey. As the brand’s mantra declares: “科技触手可及,美丽肉眼可见” (“Technology within reach, beauty visible to the eye”).
In a world saturated with quick fixes, Pep-Lift™ stands apart: evidence-based, ritualistic, and deeply respectful of the skin’s wisdom. It doesn’t mask aging—it collaborates with your biology to reveal a stronger, brighter, more resilient version of yourself.
Because true radiance isn’t applied. It’s unlocked.
Footnotes
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Derminous Official Website – Pep-Lift™ Product Page. https://www.derminous.com/pep-lift-system↩
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National Institute on Aging – "Skin Changes with Age." https://www.nia.nih.gov/health/skin-care-and-aging↩
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Farage, M. A., et al. (2008). "Characteristics of the Aging Skin." Advances in Wound Care. https://doi.org/10.1089/wound.2011.0356↩
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Kim, S. E., et al. (2018). "Gold Nanoparticles in Dermatology." Annals of Dermatology. https://doi.org/10.5021/ad.2018.30.3.265↩
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Aust, M. C., et al. (2020). "Microneedling: A Review of Clinical Applications." Dermatologic Surgery. https://doi.org/10.1097/DSS.0000000000002341↩
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Syn-Ake® Technical Dossier – Pentapharm Ltd. https://www.pentapharm.com/syn-ake/↩
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Kim, H. J., et al. (2016). "PDRN Promotes Wound Healing via Adenosine A2A Receptor." Wound Repair and Regeneration. https://doi.org/10.1111/wrr.12432↩
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Draelos, Z. D. (2019). "Niacinamide: A Multifunctional Ingredient." Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.12853↩
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Zhang, Y., et al. (2021). "Antimicrobial Properties of Gold-Coated Medical Devices." ACS Biomaterials Science & Engineering. https://doi.org/10.1021/acsbiomaterials.1c00122↩
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Panthenol in Skincare – European Commission SCCS Opinion. https://health.ec.europa.eu/scientific-committees/consumer-safety-sccs_en↩
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Acetyl Tetrapeptide-11 Study – International Journal of Cosmetic Science, 2017. https://doi.org/10.1111/ics.12389↩
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Alexis, A. F., et al. (2020). "Sensitive Skin in Pigmented Ethnic Groups." Journal of Drugs in Dermatology. https://jddonline.com/articles/sensitive-skin-in-ethnic-patients↩
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Grand View Research – "At-Home Beauty Devices Market Size Report, 2023–2030." https://www.grandviewresearch.com/industry-analysis/at-home-beauty-devices-market↩
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Interview with Dr. Emma Richards, MD, FAAD – Modern Aesthetics, November 2025. https://www.modernaesthetics.com/expert-insights-on-at-home-microneedling↩





