Micro-Channels: The Key to Deep Serum Delivery
In the evolving landscape of at-home skincare, one innovation stands out for its ability to bridge the gap between topical application and professional-grade results: micro-channeling. Unlike traditional creams that sit on the skin’s surface, micro-channeling creates temporary, microscopic pathways in the epidermis—allowing active ingredients like peptides, PDRN, and hyaluronic acid to penetrate deeply into the dermal layers where regeneration occurs[1] .

Derminous’ GeneLift™ Micro-Infusion System leverages this principle with its 24K gold-plated, medical-grade stainless steel microneedles. These ultra-fine needles (typically 0.2–0.3mm in length) gently form micro-channels without causing pain or significant trauma—making it ideal for sensitive or post-procedure skin[2] . The gold coating not only enhances biocompatibility but also provides natural antimicrobial properties, reducing inflammation and irritation risk[3] .

Clinical studies support that micro-channeling can increase transdermal delivery efficiency by up to 300% compared to passive absorption[4] . In Derminous’ proprietary protocol, this enhanced delivery is paired with a synergistic serum blend featuring PDRN (Polydeoxyribonucleotide) for tissue repair, acetyl hexapeptide-8 (a “synthetic snake venom” peptide) for wrinkle relaxation, and patented niacinamide for brightening—all clinically validated actives[5] .






The result? Immediate hydration and glow after one use, with visible improvements in firmness, texture, and radiance within 2–4 weeks when used biweekly as recommended. Crucially, the system includes a post-treatment recovery mask and lifting cream to soothe, seal, and sustain results—turning a high-tech treatment into a holistic ritual.
As consumers increasingly seek “medical-grade efficacy without the clinic,” micro-channeling represents more than a trend—it’s a paradigm shift in home skincare science.
Footnotes:
Footnotes
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National Center for Biotechnology Information (NCBI), Transdermal Drug Delivery: Principles and Applications, https://www.ncbi.nlm.nih.gov/books/NBK557591/↩
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Journal of Cosmetic Dermatology, Safety and Efficacy of At-Home Microneedling Devices, https://onlinelibrary.wiley.com/doi/10.1111/jocd.14288↩
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Materials Science and Engineering: C, Antimicrobial Properties of Gold-Coated Medical Devices, https://www.sciencedirect.com/science/article/abs/pii/S0928493119328456↩
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Dermatologic Surgery, Enhanced Penetration of Topical Agents via Microneedling, https://journals.lww.com/dermatologicsurgery/Abstract/2017/08000/Enhanced_Penetration_of_Topical_Agents_via.10.aspx↩
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International Journal of Molecular Sciences, PDRN in Skin Regeneration: Mechanisms and Clinical Evidence, https://www.mdpi.com/1422-0067/22/9/4721↩





