Unlocking Your Skin's Natural Renewal Process with Pep-Lift™
In an era where at-home skincare is no longer just about hydration or basic cleansing—but about transformation—Derminous introduces Pep-Lift™, a revolutionary micro-infusion system that brings clinical-grade anti-aging results into the comfort of your home. Designed for those who seek efficacy without compromise, Pep-Lift™ merges cutting-edge biotechnology, patented active ingredients, and a ritualistic approach to skincare to unlock your skin’s innate capacity for renewal.
The Science Behind Skin Renewal
Skin aging is a complex interplay of intrinsic (genetic) and extrinsic (environmental) factors. As we age, collagen production declines by approximately 1% per year after the age of 20[1] . Simultaneously, environmental stressors like UV radiation and pollution accelerate oxidative damage, leading to wrinkles, loss of elasticity, and uneven tone[2] .

Traditional topical skincare often struggles to penetrate the stratum corneum—the outermost barrier of the skin—limiting the delivery of active ingredients. This is where microneedling technology becomes transformative. By creating temporary microchannels, microneedling enhances transdermal absorption by up to 300%[3] , allowing high-potency actives to reach deeper layers where they can stimulate fibroblasts, boost collagen synthesis, and initiate true repair.

Pep-Lift™ leverages this principle—but with a refined, painless, and sterile twist tailored for daily life.
Introducing Pep-Lift™: A Four-Step Ritual of Renewal
Unlike conventional microneedling rollers or dermapens that require manual pressure and carry infection risks, Pep-Lift™ features a 24K gold-plated micro-infusion device engineered with medical-grade stainless steel needles. The gold coating not only adds elegance but also provides natural antimicrobial properties, reducing irritation and inflammation—critical for sensitive or post-procedure skin[4] .
The system follows a scientifically choreographed four-phase protocol:
Phase 1: Micro-Activation
The 24K gold micro-needles gently create invisible microchannels upon light pressing—no dragging, no pain. These channels remain open for 6–8 hours, offering a prolonged window for ingredient delivery[5] .
Phase 2: Precision Infusion
The accompanying GeneLift™ Serum is formulated with three patented actives:
- PDRN (Polydeoxyribonucleotide): A regenerative molecule derived from salmon DNA that accelerates tissue repair and stimulates collagen I & III synthesis[6] .
- Acetyl Hexapeptide-8 (Syn-Ake®): A biomimetic peptide that mimics the effects of botulinum toxin by inhibiting neurotransmitter release, thereby softening dynamic wrinkles[7] .
- Patented Nicotinamide (ZL2020116206743): A stabilized form of vitamin B3 that brightens skin while minimizing irritation through controlled acid content.
These ingredients work synergistically to target fine lines, dullness, and barrier weakness at the cellular level.
Phase 3: Soothing Repair
Post-infusion, the Post-Treatment Repair Mask—infused with recombinant fibronectin, mussel extract, and panthenol—calms redness, reduces transepidermal water loss (TEWL), and reinforces the skin barrier. When chilled, its cooling effect further constricts capillaries, minimizing post-treatment flushing[8] .
Phase 4: Nutrient Lock-In
The final step uses the Recovery & Lift Cream, enriched with acetyl tetrapeptide-11 (which supports skin firmness by modulating adipokine signaling[9] ), squalane, and jojoba oil. This occlusive yet breathable layer seals in actives while enhancing elasticity over time.
Why Pep-Lift™ Stands Apart in the At-Home Aesthetic Market
The global at-home beauty device market is projected to reach $54.7 billion by 2027, driven by consumer demand for professional results without clinic visits[10] . Yet many products fall short on safety, sterility, or ingredient integrity.
Pep-Lift™ addresses these gaps:
- Single-use, sterile micro-needles: Eliminates cross-contamination and bacterial buildup.
- No alcohol, fragrance, or parabens: Formulated for reactive and post-procedure skin.
- Clinically inspired, not clinically invasive: Delivers measurable improvements—87% of users report visible tightening within 4 weeks[11] —without downtime.
Moreover, Derminous adheres to a philosophy of “empowered self-care.” As the brand states: “Let every drop become a source of confidence.” This isn’t just marketing—it’s a commitment to transparency, efficacy, and respect for the skin’s biology.
Real Results, Backed by Time and Science
Clinical studies on PDRN show significant improvements in skin elasticity (+22%) and hydration (+35%) after 4 weeks of use[12] . Similarly, acetyl hexapeptide-8 has demonstrated wrinkle depth reduction of up to 30% in 30 days in double-blind trials[13] .
With Pep-Lift™, users don’t just apply skincare—they initiate a biological dialogue with their skin. Each session becomes a moment of intention: clean hands, focused touch, and potent science working in harmony.





Recommended for bi-weekly use, the system aligns with the skin’s natural turnover cycle (~28 days), ensuring cumulative benefits without overstimulation. Over time, users observe not only smoother texture and brighter tone but also a resilient, calm complexion that reflects inner balance.
The Future of Home Skincare Is Here
Derminous doesn’t merely sell a product—it offers a new paradigm: one where biotechnology meets ritual, where efficacy coexists with gentleness, and where beauty is redefined as healthy, strong, luminous skin.
As dermatologists increasingly advocate for “pre-habilitation” (preparing skin before aging signs appear)[14] , Pep-Lift™ positions itself as both a corrective and preventive tool. It’s ideal for those transitioning from injectables seeking maintenance, or for skincare enthusiasts ready to elevate their routine beyond serums and creams.
In a world saturated with quick fixes, Pep-Lift™ stands as a testament to patience, precision, and the power of cellular renewal.
Experience the future of at-home rejuvenation. Because true radiance begins beneath the surface.
Footnotes
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“Collagen Loss and Aging.” National Institute on Aging. https://www.nia.nih.gov/health/skin-care-and-aging↩
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“Environmental Skin Damage.” American Academy of Dermatology. https://www.aad.org/public/everyday-care/skin-care-secrets/routine/environmental-damage↩
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Lee, W. et al. (2017). “Microneedle-mediated transdermal delivery: Current status and future perspectives.” Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2017.08.001↩
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“Antimicrobial Properties of Gold Nanoparticles.” National Center for Biotechnology Information (NCBI). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588603/↩
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Aust, M.C. et al. (2011). “Microneedling for Skin Rejuvenation.” Journal of Cosmetic Dermatology. https://doi.org/10.1111/j.1473-2165.2011.00563.x↩
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Kim, H.S. et al. (2018). “PDRN Promotes Wound Healing via Adenosine A2A Receptor Activation.” Wound Repair and Regeneration. https://doi.org/10.1111/wrr.12632↩
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“Acetyl Hexapeptide-8: Mechanism and Efficacy.” International Journal of Cosmetic Science. https://doi.org/10.1111/j.1468-2494.2010.00572.x↩
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Draelos, Z.D. (2018). “The Role of Moisturizers in Skin Barrier Repair.” Journal of Clinical and Aesthetic Dermatology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847500/↩
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“Acetyl Tetrapeptide-11 and Skin Firmness.” Sederma (Active Ingredient Dossier). https://www.sederma.fr/en/active-ingredients/acetyl-tetrapeptide-11.html↩
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“At-Home Beauty Devices Market Size Report, 2023–2027.” Grand View Research. https://www.grandviewresearch.com/industry-analysis/at-home-beauty-devices-market↩
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Derminous Internal User Trial (2024), n=120, 4-week usage, self-reported outcomes. ↩
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Park, J.H. et al. (2020). “Efficacy of PDRN in Facial Rejuvenation.” Annals of Dermatology. https://doi.org/10.5021/ad.2020.32.3.289↩
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“Clinical Evaluation of Syn-Ake®.” Pentapharm Ltd. https://www.pentapharm.com/syn-ake/↩
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Dr. Whitney Bowe, “The Beauty of Dirty Skin.” HarperCollins, 2018. https://www.harpercollins.com/products/the-beauty-of-dirty-skin-whitney-bowe↩





