Post-Treatment Care: Why You Should Avoid Makeup for 24 Hours

Post-Treatment Care: Why You Should Avoid Makeup for 24 Hours

After undergoing advanced at-home microneedling treatments like the Derminous GeneLift™ Micro-Infusion System, your skin is in a highly receptive—but also vulnerable—state. The micro-channels created by the 24K gold-coated microneedles enhance ingredient absorption but also temporarily compromise the skin barrier^［1］ . Applying makeup too soon can introduce bacteria, clog pores, and trigger inflammation or infection, undermining the very benefits you sought from the treatment.

Dermatologists consistently advise avoiding makeup for at least 24 hours post-microneedling to allow the skin to heal and seal these micro-injuries^［2］ . Even mineral or “non-comedogenic” formulas may contain preservatives or pigments that irritate freshly treated skin. Instead, focus on gentle hydration and barrier repair—exactly what Derminous’ Post-Treatment Repair Mask and Recovery & Lift Cream are formulated for, featuring soothing ingredients like panthenol, recombinant fibronectin, and centella asiatica extracts.

Moreover, skipping makeup gives active ingredients like PDRN (Polydeoxyribonucleotide) and acetyl hexapeptide-8 time to work undisturbed, maximizing collagen stimulation and wrinkle reduction^［3］ . As noted by the American Academy of Dermatology, post-procedure care is as critical as the treatment itself for achieving safe, visible results^［4］ .

In short: let your skin breathe, heal, and glow—naturally—for at least one full day. Your future complexion will thank you.