PDRN and Peptides: The Power Duo in DerMinous Pep-Lift™ Serum
In the evolving world of at-home skincare innovation, few ingredients command as much scientific respect—and consumer fascination—as Polydeoxyribonucleotide (PDRN) and bioactive peptides. At the heart of DerMinous’ flagship Pep-Lift™ 24K Gold Micro-Infusion System lies a synergistic fusion of these two powerhouse actives, engineered to deliver clinical-grade anti-aging results without needles, downtime, or irritation.
PDRN, derived from salmon DNA, is a regenerative compound long used in wound healing and dermatological treatments. It stimulates fibroblast activity, boosts collagen synthesis, and accelerates tissue repair—making it ideal for post-microneedling recovery and barrier restoration[1] . Clinical studies have shown PDRN’s efficacy in improving skin elasticity and hydration within weeks of consistent use[2] .

Complementing PDRN are multi-peptide complexes, including Acetyl Hexapeptide-8 (Syn-Ake®) and Dipeptide Diaminobutyroyl Benzylamide Diacetate, which mimic neuromodulating effects to relax facial muscles and reduce dynamic wrinkles—often dubbed “Botox-like” without injection[3] . Additionally, Arginine/Lysine Polypeptide enhances microcirculation and supports extracellular matrix integrity.
DerMinous’ proprietary serum combines these with patented Nicotinamide (ZL2020116206743) for brightening and Soluble Collagen for structural support, all delivered via a 24K gold-coated micro-infusion device that enhances transdermal absorption by up to 3x[4] . The result? A painless, at-home ritual that bridges the gap between cosmetic skincare and medical aesthetics.
Backed by clean, fragrance-free formulation and tailored for sensitive and post-procedure skin, the Pep-Lift™ Serum exemplifies how molecular science can be harnessed for daily empowerment—proving that true radiance begins with cellular renewal.
Footnotes
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Polydeoxyribonucleotide (PDRN): Mechanism and Applications in Dermatology, Journal of Cosmetic Dermatology – https://onlinelibrary.wiley.com/doi/10.1111/jocd.13567↩
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Efficacy of PDRN in Skin Rejuvenation: A Randomized Controlled Trial, Dermatologic Surgery – https://journals.lww.com/dermatologicsurgery/Abstract/2020/05000/Efficacy_of_PDRN_in_Skin_Rejuvenation__A.10.aspx↩
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Acetyl Hexapeptide-8: A Topical Alternative to Botulinum Toxin?, International Journal of Cosmetic Science – https://ifsciences.org/ijcs/volume-42-issue-3-june-2020/acetyl-hexapeptide-8-a-topical-alternative-to-botulinum-toxin↩
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Transdermal Delivery Enhancement via Microneedling with Gold-Coated Tips, Advanced Drug Delivery Reviews – https://www.sciencedirect.com/science/article/pii/S0169409X21001234↩





